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Tocilizumab Recombinant Human Monoclonal Antibody (rhPM-1 (Tocilizumab)), Invitrogen™
Human Recombinant Monoclonal Antibody
Marque: Invitrogen MA548061
345.35 EUR valable jusqu'au 2025-03-21
Utilisez le code promo "24111" pour bénéficier de cette offre.
Alert:
Pour que la promotion s’applique, le client doit acheter trois fois le même produit au prix catalogue sur la même commande pour avoir une remise de 33.33%. Il n’y a pas de limite d’achat pour un multiple de 3 produits. PCODE: 24111
Description
Specificity: Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann-La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
Spécification
| Tocilizumab | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| Human | |
| Affinity chromatography | |
| RUO | |
| Human | |
| Liquid |
| ELISA, Inhibition Assays | |
| rhPM-1 (Tocilizumab) | |
| Unconjugated | |
| IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533 | |
| This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions. | |
| 200 μg | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| IgG1 κ |
Promotions
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Plusieurs fabricants
Plus de découvertes, moins de coûts
Économisez sur des milliers de produits éligibles.Code promotionnel: 24111Expire: 2025-03-21
Nouvelle offre Économisez maintenant
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Nom du produit
Tocilizumab Recombinant Human Monoclonal Antibody (rhPM-1 (Tocilizumab)), Invitrogen™ > 200 μg; Unconjugated
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