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Cortisol Monoclonal Antibody (BGN/C42), Invitrogen™
Mouse Monoclonal Antibody
Marque: Invitrogen MA183088
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Description
MA1-83088 recognizes cortisol and corticosterone and does not cross-react with cortisone or progesterone.
Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Spécification
| Cortisol | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.09% sodium azide | |
| Cortisol conjugated to BSA. | |
| 200 μg | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid | |
| Chemical |
| ELISA | |
| BGN/C42 | |
| Unconjugated | |
| Mouse | |
| Protein A | |
| RUO | |
| Chemical | |
| Antibody | |
| IgG1 |