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APC13 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marque: Invitrogen PA561154
369.35 EUR valable jusqu'au 2025-03-29
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Description
Immunogen sequence: MDSEVQRDGR ILDLIDDAWR EDKLPYEDVA IPLNELPEPE QDNGGTTESV KEQEMKWTDL ALQYLHENVP Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
Spécification
APC13 | |
Polyclonal | |
Unconjugated | |
ANAPC13 | |
1810004D07Rik; ANAPC13; anaphase promoting complex subunit 13; anaphase-promoting complex subunit 13; APC13; cyclosome subunit 13; cylosome subunit 13; SWM1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
25847 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry, Western Blot | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9BS18 | |
ANAPC13 | |
Recombinant protein corresponding to Human APC13 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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