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AKR1C1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marque: Invitrogen PA521672
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Description
Recommended positive controls: A431, HeLa, HepG2, A549, mouse liver. Predicted reactivity: Pig (83%), Rhesus Monkey (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Spécification
| AKR1C1 | |
| Polyclonal | |
| Unconjugated | |
| AKR1C1 | |
| 17-beta-HSD 5; 17HSD type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3alpha-HSD; Akr1c1; Akr1c6; aldo-keto reductase C; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (aldehyde reductase); aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; estradiol 17 beta-dehydrogenase 5; estradiol 17-beta-dehydrogenase (A-specific); H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity hepatic bile acid-binding protein; Hsd17b5; hydroxysteroid 17-beta dehydrogenase 5; indanol dehydrogenase; MBAB; RP11-69D4.1; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type 5 17beta-hydroxysteroid dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1645, 83702 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.6 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P70694, Q04828 | |
| AKR1C1, Akr1c6 | |
| Recombinant fragment corresponding to a region within amino acids 22 and 248 of AKR1C1 (Uniprot ID#Q04828) | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Nom du produit
AKR1C1 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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