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PP 121
Dual kinase inhibitor; inhibits PI 3-K family kinases
Marque: Tocris 3894/5
Code nomenclature Nacres: NA.26
Informations supplémentaires : Poids : 0.00970kg
Description
PP 121 is a dual inhibitor of receptor tyrosine kinases (RTKs) (IC50 < 0.02 μM for Abl, Src, VEGFR-2 and PDGFR) and PI 3-K family kinases (IC50 < 0.06 μM for p110α, DNA-PK and mTOR). Exhibits no significant effect on receptor serine/threonine kinases (RSTKs). Blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor.Spécification
| 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | |
| >99% | |
| C17H17N7 |
| 1092788-83-4 | |
| 5 mg | |
| Observed MW: 319.36 |