missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ CY 09
Inflammasomes Inhibitors
Marque: Tocris Bioscience™ 6436/50
Code nomenclature Nacres: NA.26
Informations supplémentaires : Poids : 0.00970kg
Description
CY 09 is a NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM).Spécification
| 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid | |
| 50 mg | |
| 98% |
| 1073612-91-5 | |
| C19H12F3NO3S2 |