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ZFYVE21 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 24806-1-AP-20UL
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Description
ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.Spécification
| ZFYVE21 | |
| Polyclonal | |
| Unconjugated | |
| ZFYVE21 | |
| ZFYVE21 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 79038 | |
| -20°C | |
| Liquid |
| Western Blot, Immunoprecipitation | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q9BQ24 | |
| ZFYVE21 | |
| ZFYVE21 Fusion Protein Ag20024 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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