missing translation for 'onlineSavingsMsg'
Learn More

Thermo Scientific Chemicals U-73122, 95 %

Code produit. 15475189
Click to view available options
Quantité:
1 mg
5 mg
10 mg
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

It is used as a phospholipase C, phospholipase A2, and 5-LO inhibitor. It is also determined that in SK-N-SH neuroblastoma cells, U-73122 inhibits agonist-induced down-regulation of muscarinic receptors. In addition, it is a useful tool to investigate receptor-mediated PI turnover in signal transduction. U-73122 is a potent inhibitor of human neutrophil adhesion to biological surfaces (IC50 = 50 nM) as well as adhesion-dependent granule exocytosis and oxidative burst. U-73343 (sc-201422) is useful as a negative control for investigations of U-73122 phospholipase C antagonism and its cellular consequences.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Inhibiteur de l’activation de la phospholipase C et inhibe la régulation descendante des récepteurs muscariniques
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 112648-68-7
Formule moléculaire C29H40N2O3
Synonyme 1-[6-[((17beta)-3-Methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]pyrrole-2,5-dione

Specifications

Quantité 10 mg
Description Blanc cassé
À utiliser avec (application) Inhibiteur de l’activation de la phospholipase C et inhibe la régulation descendante des récepteurs muscariniques
Doser ≥ 99%
Poids de la formule 464,65g/mol
Solubilité Soluble dans le DMSO, l’éthanol ou le DMF à environ 0,5 mg/ml ; peut nécessiter un chauffage ou un mélange pendant la nuit ; insoluble dans l’eau
Type de produit Réactif de transduction de signal
Forme Solide cristallin
Clé InChI LUFAORPFSVMJIW-ZRJUGLEFSA-N
SMILES COC1=CC=C2[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CCC2=C1)NCCCCCCN1C(=O)C=CC1=O
Nom IUPAC 1-(6-{[(1S,3aS,3bR,9bS,11aS)-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]amino}hexyl)-2,5-dihydro-1H-pyrrole-2,5-dione
Poids moléculaire (g/mol) 464.65
Show More Show Less

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.