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Taxol, Tocris Bioscience™

Code produit. 30001192

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10 mg

50 mg

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Description

Promotes assembly and inhibits disassembly of microtubules

Taxol, also known as paclitaxel, promotes and stabilizes tubulin polymerization, causing cell cycle arrest. In CCRF-HSB-2 cells, Taxol induces autocatalytic activation of caspase-10, triggering apoptosis. Taxol is an antitumor agent. In a mouse model of bladder cancer Taxol decreases tumor growth. Taxol also prolongs survival of mice transplanted with human ovarian carcinoma xenografts. Taxol improves neurological outcome and magnetic resonance imaging biomarkers after traumatic brain injury in mice.

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Identifiants chimiques

CAS	33069-62-4
Formule moléculaire	C47H51NO14
Poids moléculaire (g/mol)	853.92
Numéro MDL	MFCD00869953
Clé InChI	RCINICONZNJXQF-VAZQATRQSA-N
Synonyme	paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel
CID PubChem	133640187
Nom IUPAC	(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
SMILES	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1

Spécification

Nom chimique ou matériau	Taxol
Quantité	10 mg
Poids de la formule	853.92
Pourcentage de pureté	>99%

Taxol, Tocris Bioscience™

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Identifiants chimiques

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