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Invitrogen™ S1P1 Recombinant Rabbit Monoclonal Antibody (4F2)
Rabbit Recombinant Monoclonal Antibody
Marque: Invitrogen™ MA538397
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Description
This antibody has been tested in direct-ELISA.
S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.
Spécification
| S1P1 | |
| Recombinant Monoclonal | |
| 0.44 mg/mL | |
| PBS with 50% glycerol, 150mM NaCl and 0.02% sodium azide; pH 7.4 | |
| P21453 | |
| S1PR1 | |
| A synthesized peptide derived from human EDG1 (aa 7-21). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| 4F2 | |
| Unconjugated | |
| S1PR1 | |
| AI849002; CD antigen CD363; CD363; CD363 antigen; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; EDG1 (Edg1); Edg1; rhodopsin family G protein-coupled receptor; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; etID43307.22; Lpb1; Lysophospholipid receptor B1; S1p; S1P receptor 1; S1P receptor Edg-1; s1p1; S1PR1; sphingosine 1-phosphate receptor; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1; wu:fb98f05 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 1901 | |
| -20°C or -80°C if preferred | |
| Liquid |
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