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PF 04620110, Tocris Bioscience™
Potent and selective DGAT-1 inhibitor; orally bioavailable
Marque: Tocris 5863/5
Informations supplémentaires : Poids : 0.00970kg
Description
PF 04620110 is a potent and selective DGAT-1 inhibitor (IC50 = 19 nM). Exhibits >1000-fold selectivity for DGAT-1 over DGAT-2, and no significant activity against a range of other enzymes, ion channels and receptors. Reduces plasma triglyceride levels in a rat lipid challenge model. Orally bioavailable.Spécification
| trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]cyclohexaneacetic acid | |
| 1109276-89-2 | |
| >98% | |
| 5 mg |