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MYLK3 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | MYLK3 |
---|---|
Concentration | 0.22 mg/mL |
Applications | Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16891115
|
Proteintech
21527-1-AP-20UL |
20 μL |
140.00€
20µL |
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16881115
|
Proteintech
21527-1-AP-150UL |
150 μL |
399.00€
150µL |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
Description
MLCK, a member of the Ser/Thr protein kinase family, is a calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments. It is a central determit in the development of vascular permeability and tissue edema formation. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis. Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the domit splice variant expressed in various tissues. The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues. MLCK is probably down-regulated by phosphorylation. The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.Spécification
MYLK3 | |
Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence | |
Unconjugated | |
Rabbit | |
Human | |
Q32MK0 | |
91807 | |
MYLK3 Fusion Protein Ag16137 | |
Primary | |
-20°C | |
MYLK3 |
0.22 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
caMLCK, MLCK, MLCK2, MYLK3, myosin light chain kinase 3 | |
MYLK3 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |