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Invitrogen™ Mouse Urokinase ELISA Kit
For the quantitative detection of Mouse Urokinase
Marque: Invitrogen™ EEL113
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Description
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Spécification
P06869 | |
9.38 pg/mL | |
ELISA | |
Colorimetric Microplate Reader | |
PLAU | |
<10% | |
HRP | |
RUO | |
Refer to product documentation for component specific storage temperature. | |
1 hr 20 min |
15.63 to 1000 pg/mL | |
HRP | |
Plasma | |
18792 | |
<10% | |
Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer | |
96 Tests | |
100 µL | |
Mouse | |
3 hr 30 min |