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Metformin hydrochloride, Tocris Bioscience™
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Quantité:
100 mg
Description
Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.
Spécification
| Nom chimique ou matériau | Metformin hydrochloride |
| CAS | 1115-70-4 |
| Formule moléculaire | C4H12ClN5 |
| Numéro MDL | MFCD00012582 |
| Quantité | 100 mg |
| Synonyme | metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform |
| Clé InChI | OETHQSJEHLVLGH-UHFFFAOYSA-N |
| SMILES | [H+].[Cl-].CN(C)C(=N)N=C(N)N |
| Nom IUPAC | hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride |
| Poids moléculaire (g/mol) | 165.63 |
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