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Cytiva™ MabSelect™ VL Protein L Resin
The MabSelect™ VL resin is a protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Marque: Cytiva™ 17542001
Description
MabSelect™ VL resin with a redesigned protein L ligand for high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
- High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Spécification
25 mL | |
Alkaline Stabilized Protein L-derived (E. coli) | |
60 μm | |
Chromatographie d’affinité des anticorps |
300 cm/hr. | |
2 à 10 | |
2°C to 8°C, 20% Ethanol | |
VL Protein L Resin |
Sécurité et traitement
- MabSelect VL, 25 ml
Mention d'avertissement
- Attention
Catégorie de danger
- Liquide inflammable Catégorie 3
Mention de danger
- H226-Liquide et vapeurs inflammables.
Conseils de prudence
- P210-Tenir à l'écart de la chaleur, des surfaces chaudes, des étincelles, des flammes nues et de toute autre source d'inflammation. Ne pas fumer.
- P501b-Éliminer le contenu/récipient conformément à la réglementation locale/régionale/nationale/internationale.
Informations supplémentaires
- MIXTURE LIST-Contient: ethanol
- UNKNOWN ACUTE-Le mélange contient 16.5% de composants dont la toxicité aiguë est inconnue.