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LMX1B Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marque: Invitrogen PA567308
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.01000kg
Description
Immunogen sequence: DIATGPESLER CFPRGQTDCA KMLDGIKMEE HALRPGPATL GVLLGSDCPH PAVCEGCQRP ISDRFL Highest antigen sequence identity to the following orthologs - mouse 67%, rat 100%.
LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.Spécification
| LMX1B | |
| Polyclonal | |
| Unconjugated | |
| Lmx1b | |
| LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.1; LMX1.2; LMX-1.2; LMX1B; NPS1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4010 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O60663 | |
| Lmx1b | |
| Recombinant Human LMX1B | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
For Research Use Only