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LKB1 Monoclonal Antibody (B.593.0), Invitrogen™
Rabbit Monoclonal Antibody
Marque: Invitrogen MA514942
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.01000kg
Description
It is not recommended to aliquot this antibody.
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.Spécification
| LKB1 | |
| Monoclonal | |
| Unconjugated | |
| STK11 | |
| AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 6794 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| B.593.0 | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5 | |
| Q15831 | |
| STK11 | |
| Synthetic peptide corresponding to the sequence of human LKB1 | |
| 100 μL | |
| Primary | |
| Human, Non-human Primate | |
| Antibody | |
| IgG |