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KT 5720, Tocris Bioscience™
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Quantité:
100 μg
Description
Potent, selective inhibitor of protein kinase A (Ki = 60 nM). Has no effect on PKG or PKC (Ki > 2 μM). Reversibly arrests human skin fibroblasts in the G1 phase.
Spécification
Spécification
| Nom chimique ou matériau | KT 5720 |
| CAS | 108068-98-0 |
| Formule moléculaire | C32H31N3O5 |
| Numéro MDL | MFCD00132118,MFCD11867896 |
| Quantité | 100 μg |
| Synonyme | unii-58hv29i28s, insolution kt5720, 9r,10s,12s-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid hexyl ester, 9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, hexyl ester, 9r,10r,12s-rel, ambotzls-1036, antibiotic kt 5720, 9s,10s,12r-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid hexyl ester, 9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, hexyl ester, 9alpha,10beta,12alpha, hexyl hydroxy-methyl-oxo-? carboxylate |
| Clé InChI | ZHEHVZXPFVXKEY-RUAOOFDTSA-N |
| SMILES | CCCCCCOC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)N1C3=C(C=CC=C3)C3=C1C1=C(C4=CC=CC=C4N21)C1=C3CNC1=O |
| Nom IUPAC | hexyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),7(27),8(13),9,11,20,22,24-nonaene-16-carboxylate |
| Poids moléculaire (g/mol) | 537.62 |
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