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Invitrogen™ KAL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marque: Invitrogen™ PA5101428
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Description
Antibody detects endogenous levels of total KAL1.
KAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
Spécification
| KAL1 | |
| Polyclonal | |
| Unconjugated | |
| ANOS1 | |
| Adhesion molecule-like X-linked; ADMLX; ANOS1; anosmin; anosmin 1; Anosmin1; anosmin-1; HH1; HHA; KAL; KAL1; KALIG1; KALIG-1; Kallmann syndrome interval gene 1; kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); KMS; WAP four-disulfide core domain 19; WFDC19 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 3730 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P23352 | |
| ANOS1 | |
| A synthesized peptide derived from human ANOS1(Accession P23352), corresponding to amino acid residues K162-I212. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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