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Gibco™ Human VEGF-165 Recombinant Protein, PeproTech®

Code produit. 17800953
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Quantité:
1 mg
10 μg
100 μg
2 μg
250 μg
50 μg
500 μg
Conditionnement:
100µg
10µg
1mg
250µg
2µg
500µg
50µg
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Product Code. 17800953

missing translation for 'mfr': Gibco™ 100201MG

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2691.00 EUR valable jusqu'au 2025-12-19
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Description

Recombinant Protein

Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Numéro d’adhésion P15692
À utiliser avec (application) ELISA, Functional Assay, Western Blot
Formule protein with no preservative
Identification génétique (Entrez) 7422
Poids moléculaire 38.2 kDa
Nom Human VEGF-165
Quantité 1 mg
Source E. coli
État réglementaire RUO
Concentration en endotoxines <1 EU/ μg
Alias de gène H-VEGF-165; MVCD1; M-VEGF-165; vascular endothelial growth factor 165 b; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF164; VEGF165; Vegfa; VEGF-A; VPF
Nom usuel VEGF-165
Symbole de gène(s) VEGFA
Activité biologique Determined by its ability to stimulate the proliferation of human umbilical vein endothelial cells (HUVEC). The expected ED50 for this effect is 1.0-10.0 ng/ml
Conjugué Unconjugated
Recombinant Recombinant
Séquence APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Contenu et stockage -20°C
Système d’expression E. coli
Forme Lyophilized
Pureté ou qualité ≥ 98% by SDS-PAGE gel and HPLC analyses.
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