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Cytiva™ HiTrap™ Chromatography Columns with MabSelect™ VL Protein L Resin
Protein L affinity chromatography columns for capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Marque: Cytiva™ 17542053
Code nomenclature Nacres: NA.56
Informations supplémentaires : CAS : 64-17-5 Poids : 0.08550kg
Description
- Redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability
- High dynamic binding capacity for efficient capture of target molecules
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Specifications
| 5 mL | |
| 16 mm | |
| 1 in. | |
| <20 mL/min. | |
| Affinity Column |
| 0.63 in. | |
| 1 x 5 mL | |
| 25 mm | |
| 5 bar | |
| Antibody Affinity Chromatography |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- HiTrap MabSelect VL, 1 x 5 ml
Signal Word
- Attention
Hazard Category
- Liquide inflammable Catégorie 3
Hazard Statement
- H226-Liquide et vapeurs inflammables.
Precautionary Statement
- P210-Tenir à l'écart de la chaleur, des surfaces chaudes, des étincelles, des flammes nues et de toute autre source d'inflammation. Ne pas fumer.
- P501b-Éliminer le contenu/récipient conformément à la réglementation locale/régionale/nationale/internationale.
Supplemental information
- MIXTURE LIST-Contient: ethanol
- UNKNOWN ACUTE-Le mélange contient 16.5% de composants dont la toxicité aiguë est inconnue.