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Tocris™ GRL 0617
Coronavirus PLpro inhibitor
Marque: Tocris™ 7280/25
Code nomenclature Nacres: NA.26
Informations supplémentaires : Poids : 0.00970kg
Description
GRL 0617 is a coronavirus papain-like protease (Plpro) inhibitor (IC50 values are 0.6 and 0.8 μM for SARS-COV and SARS-CoV-2 PLpro, respectively). Inhibits deubiquitination activity of SARS-CoV PLpro. Displays no inhibition of human deubiquitinating enzymes. Improves cell viability following SARS-CoV infection. Inhibits SARS-CoV-2 viral replication and induces antiviral immune signaling pathways following SARS-CoV-2 infection in CaCo-2 cells.Spécification
| 5-Amino-2-methyl-N-[(1 R)-1-(1-naphthalenyl)ethyl]benzamide | |
| 25 mg | |
| C20H20N2O |
| 1093070-16-6 | |
| Papain-like Protease Inhibitors | |
| 0.98 |