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Deoxynivalenol, Tocris Bioscience™
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Quantité:
1 mg
Description
Tricothecene mycotoxin and potent protein synthesis inhibitor. Exhibits cytotoxic activity in vivo via the ribotoxic stress response. Induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.
Spécification
| Nom chimique ou matériau | Deoxynivalenol |
| CAS | 51481-10-8 |
| Formule moléculaire | C15H20O6 |
| Numéro MDL | MFCD09039270 |
| Quantité | 1 mg |
| Synonyme | deoxynivalenol, vomitoxin, dehydronivalenol, 4-deoxynivalenol, 4-desoxynivalenol, desoxynivalenol, unii-jt37hyp23v, ccris 7801, rd toxin, jt37hyp23v |
| Clé InChI | LINOMUASTDIRTM-QGRHZQQGSA-N |
| SMILES | CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]33CO3)[C@@]2(CO)[C@H](O)C1=O |
| Nom IUPAC | (1'R,2S,2'R,3'S,7'R,9'R,10'R)-3',10'-dihydroxy-2'-(hydroxymethyl)-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0²,⁷]dodecan]-5'-en-4'-one |
| Poids moléculaire (g/mol) | 296.32 |
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