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Chitotriosidase Monoclonal Antibody (1D9G2,1D9G4,2B4G3), Invitrogen™
Mouse Monoclonal Antibody
Marque: Invitrogen MA515482
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Description
MA5-15482 targets CHIT1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15482 immunogen is purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.<br>.
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Spécification
| Chitotriosidase | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| Q13231 | |
| CHIT1 | |
| Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli. | |
| RUO | |
| 1118 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Western Blot | |
| 1D9G2,1D9G4,2B4G3, 1D9G4, 2B4G3 | |
| Unconjugated | |
| CHIT1 | |
| 2300002L19Rik; CHI3; CHIT; Chit1; CHITD; chitinase 1; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |