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Ch 55, Tocris Bioscience™

Code produit. 18055162

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10 mg

50 mg

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Description

Potent RAR agonist

Highly potent synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM).

Spécification

Identifiants chimiques

CAS	110368-33-7
Formule moléculaire	C24H28O3
Poids moléculaire (g/mol)	364.485
Clé InChI	FOUVTBKPJRMLPE-FMIVXFBMSA-N
Synonyme	3,5-di-tert-butylchalcone, 4-1e-3-3,5-di-tert-butylphenyl-3-oxoprop-1-en-1-yl benzoic acid, 4-3-3,5-di-t-butylphenyl-3-oxo-1-propenyl benzoic acid, e-4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl benzoic acid, benzoic acid, 4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl-, e, 3,5-di-tert-butylchalcone-4'-carboxylic acid, e-4-3,5-di-t-butylphenyl-3-oxopropenyl benzoic acid, 4-3-3,5-di-tert-butylphenyl-3-oxo-1-propenyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxo-prop-1-enyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxoprop-1-enyl benzoic acid
CID PubChem	6184667
Nom IUPAC	4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid
SMILES	CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C

Spécification

Nom chimique ou matériau	Ch 55
Quantité	10 mg
Poids de la formule	364.47
Pourcentage de pureté	>98%

Ch 55, Tocris Bioscience™

Description

Spécification

Identifiants chimiques

Spécification

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