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CDC25A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 55031-1-AP-20UL
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Description
The antibody is specific to CDC25A.
Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism, including DNA replication, DNA repair and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus and loads proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotidebinding consensus sequences. Four of the five RFC genes (RFC1, RFC2, RFC3 and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC2, the third-largest subunit of the RFC complex, exhibits ATP binding which makes it important for both DNA replication and checkpoint function.Spécification
| CDC25A | |
| Polyclonal | |
| Unconjugated | |
| CDC25A | |
| CDC25A, CDC25A2, M phase inducer phosphatase 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 12530, 993 | |
| -20°C | |
| Liquid |
| Western Blot, Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| 0.53 mg/mL | |
| 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P30304, P48964 | |
| Cdc25a | |
| Peptide | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |