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CD132 Mouse anti-Human, PE, Clone: AG184, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 555900
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Description
TheAG184 monoclonal antibody specifically binds to the 65-70 kDa common γ subunit (γc) that is shared by the IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptor complexes. The γc receptor is a type 1 transmembrane glycoprotein that is constitutively expressed by most peripheral T and B lymphocytes, NK cells, monocytes and granulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analyses, the AG184 antibody has been shown to specifically recognize human γc expressed by cell lines including human γc gene-transfected cell lines which are known to express the human γc chain. The AG184 antibody can bind the γc chain in the receptors complexed with IL-2, IL-4, or IL-7, indicating that the antibody recognizes an epitope which is distinct from the cytokine binding site of the γc chain.
Spécification
| CD132 | |
| Monoclonal | |
| 0.2mg/mL | |
| IL2RG; IL-2RG; IL-2Rγ; Common gamma chain; γc; CIDX; SCIDX; SCIDX1; IMD4 | |
| Mouse | |
| 0.2 mg | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| AG184 | |
| PE | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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Nom du produit
For Research Use Only.
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