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Calsequestrin 2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 27560-1-AP-20UL
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Description
Calsequestrin 2 (CASQ2) specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. CASQ2 is an important component of calcium handling as a calcium storage protein in the sarcoplasmic reticulum (SR), playing an important role in the regulation of the cardiac ryanodine receptor (RyR2)-mediated calcium release and SR calcium release refractoriness. Mutations in CASQ2 cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. .Spécification
| Calsequestrin 2 | |
| Polyclonal | |
| Unconjugated | |
| CASQ2 | |
| Calsequestrin 2, CASQ2, PDIB2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 12373, 845 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O09161, O14958 | |
| Casq2 | |
| Calsequestrin 2 Fusion Protein Ag26412 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |
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