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AURKC (Aurora C) Recombinant Human Protein
AURKC (Aurora C) Protein
Marque: Invitrogen PV3856
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Description
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
Spécification
| AAH75064 | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 61.7kDa | |
| 10 μg | |
| For research use only. Not for use in diagnostic procedures | |
| AURKC (Aurora C) Recombinant Human Protein | |
| Aurora | |
| 33nmoles of phosphate transferred to Kemptide peptide substrate (LRRASLG) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.3μg/mL | |
| GST Tag | |
| Kinase and inhibitors | |
| 80% by SDS-PAGE |
| 0.23mg/mL | |
| 10488, 6795 | |
| AURKC (Aurora C) Recombinant Human Protein | |
| –80°C | |
| AURKC (Aurora C), Aurora A, STK13 | |
| AURKC (aurora C) was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL kemptide peptide substrate (LRRASLG) and trace [ 32P]-γ-ATP for 10 minutes at 30°C | |
| AURKC (Aurora C) Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Serine/threonine kinase |
For Research Use Only. Not for use in diagnostic procedures.