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Invitrogen™ SUZ12 Monoclonal Antibody (3D10)
Mouse Monoclonal Antibody
Marque: Invitrogen™ MA515733
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Description
MA5-15733 targets SUZ12 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15733 immunogen is purified recombinant fragment of human SUZ12 expressed in E. Coli. MA5-15733 detects SUZ12 which has a predicted molecular weight of approximately 83.1kDa.
SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
Spécification
| SUZ12 | |
| Monoclonal | |
| Conc. Not Determined | |
| Ascites with 0.03% sodium azide | |
| Q15022 | |
| SUZ12 | |
| Purified recombinant fragment of human SUZ12 expressed in E. Coli. | |
| RUO | |
| 23512 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 3D10 | |
| Unconjugated | |
| SUZ12 | |
| 2610028O16Rik; AI195385; AU016842; AW536442; chET 9 protein; CHET9; chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; Kiaa0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog; suppressor of zeste 12 homolog (Drosophila); suppressor of zeste 12 protein homolog; Suz12; SUZ12 polycomb repressive complex 2 subunit | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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