missing translation for 'onlineSavingsMsg'
Learn More
Learn More
RORγt Mouse anti-Human, PE, Clone: Q21-559, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 563081
This item is not returnable.
View return policy
Description
The Q21-559 monoclonal antibody recognizes ROR gamma t (RORγt), an isoform of RORgamma (RORγ). RORγt is a DNA-binding transcription factor that is encoded by the RORC (RAR-related orphan receptor C) gene. It belongs to the ROR/RZR orphan nuclear receptor family. Two protein isoforms are produced from the RORC gene by alternative splicing: RORγγt is highly restricted to the thymus where it is expressed exclusively in immature CD4+CD8+ thymocytes and in peripheral Th17 and LTi cells. RORγt reportedly functions as an essential transcription factor for the development of secondary lymphoid tissues. It also plays an important regulatory role in thymopoiesis and effector T cell differentiation, especially for Th17 cells.
Specifications
| RORγt | |
| Monoclonal | |
| PE | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human RORγt Recombinant Protein | |
| 50 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| Q21-559 | |
| RORgt; ROR gamma t; RORC; NR1F3; RORG; RZRG; TOR; RZR-GAMMA | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG2b κ |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction