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CD11b/Mac-1 Mouse anti-Human, APC, Clone: ICRF44, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 550019
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Description
Reacts with the 165kDa adhesion glycoprotein (Mac-1, integrin αM subunit) which associates with the 95kDa integrin β2 (CD18) to form the CD11b/CD18 complex. CD11b/Mac-1 is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and as a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits PMN aggregation in response to fMLP. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Mouse
Clone: ICRF44
Isotype: IgG1, κ
Cross Reactivity: Human
Flow Cytometry
Spécification
| CD11b | |
| Monoclonal | |
| APC | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human monocytes | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| ICRF44 | |
| MAC-1A; Mac-1; ITGAM; Integrin alpha M; CR3A; CR-3 alpha; Mo1; SLEB6 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.