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Alpha-2-macroglobulin Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 13545-1-AP-20UL
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Description
Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregcy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer′s disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.Spécification
| Alpha-2-macroglobulin | |
| Polyclonal | |
| Unconjugated | |
| A2M | |
| A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, FWP007, S863 7, alpha-2M | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 2 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P01023 | |
| A2M | |
| Alpha-2-macroglobulin Fusion Protein Ag4489 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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