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Invitrogen™ Acetyl-CoA Carboxylase Monoclonal Antibody (B.800.8)
Rabbit Monoclonal Antibody
Marque: Invitrogen™ MA515025
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Description
It is not recommended to aliquot this antibody.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Spécification
| Acetyl-CoA Carboxylase | |
| Monoclonal | |
| 210 μg/mL | |
| 0.01M HEPES with 0.15M NaCl, 50% glycerol, 100 μg/mL BSA and <0.02% sodium azide; pH 7.5 | |
| P11497, Q13085, Q5SWU9 | |
| Acaca, ACC | |
| Synthetic peptide corresponding to residues surrounding Ser523 of human acetyl-CoA carboxylase a1. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Hamster | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| B.800.8 | |
| Unconjugated | |
| Acaca | |
| A1Z784_DROME; A530025K05Rik; Acac; Acaca; ACACAD; Acc; ACC1; ACCA; ACC-alpha; ACC-PA; ACC-PB; ACC-PC; ACC-PE; ACC-PF; ACC-PG; aceto-acetyl-CoA-thiolase; acetyl CoA carboxylase; acetyl coenzyme A carboxylase; Acetyl-CoA carboxylase; Acetyl-CoA carboxylase 1; acetyl-CoA carboxylase 265; acetyl-CoA carboxylase alpha; acetyl-CoA-carboxylase; acetyl-coenzyme A carboxylase; acetyl-coenzyme A carboxylase alpha; ACoT; Biotin carboxylase; CG11198; CG11198-PA; CG11198-PB; CG11198-PC; CG11198-PE; CG11198-PF; CG11198-PG; CG8723; dACC; DmACC; Dmel\CG11198; Dmel_CG11198; EC 6.3.4.14; EC 6.4.1.2; FBgn0043811; GH12002p; Gm738; I79_006999; unnamed protein product | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 100762904, 104371, 107476, 31, 60581 | |
| -20°C | |
| Liquid |
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