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Tocris Bioscience™ (+/-)-a-Lipoamide, Liquid-Liquid Phase Separated
Liquid-liquid phase separated condensate modifier; reduces stress granule formation
Marque: Tocris Bioscience™ 7044/100
101.08 EUR valable jusqu'au 2024-12-16
Utilisez le code promo "21630" pour bénéficier de cette offre.
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Description
(±)-α-Lipoic acid (ALA) is a liquid-liquid phase separated condensate modifier. Reduces stress granule formation in HeLa cells. Also stimulates mitochondrial biogenesis in 3T3-L1 adipocytes. Prevents dieback of FUS mutant motor neurons in culture and reverses motor defects in D. melanogaster expressing mutated human FUS. (±)-α-Lipoic acid is also an antixocidant. In hematopoietic stem cells (HSC) (±)-α-Lipoic acid reduces levels of reactive oxygen species (ROS) and inhibits apoptosis. It also promotes the generation of hematopoietic stem/progenitor cells from hPSCs in vitro and maintenance of functional cord blood HSCs ex vivo.Spécification
| 1,2-Dithiolane-3-pentanoic acid | |
| 100 mg | |
| 98% |
| 1077-28-7 | |
| C8H14O2S2 |