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Thermo Scientific™ 2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

Marque:  Thermo Scientific™ 27-1607-12

Code produit. 17927192

  • 42.10€ / 500mg

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Description

Description

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C44H53FN7O8P
Base: G
Base Protection: iBu
Formula weight: 857.4 g/mol
CAS number: 144089-97-4
HPLC purity: >98%
31P NMR purity: ≥98%

TRUSTED_SUSTAINABILITY
Spécification

Spécification

Synthétiseurs MerMade
Conserver dans le congélateur (à -20°C ou moins).
2in-Fluoro modifié
98%
Phosphoramidite
ARN
2in-Fluoro-iBu-G CEP
Guanosine (G)
Température ambiante
0.5 g
Étalon
Poudre
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Usage exclusivement réservé à la recherche. Ne pas utiliser pour des procédures de diagnostic.