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Thermo Scientific™ TheraPure™ 2'-Fluoro-Ac-C Phosphoramidite, 28-400 finish bottle

2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

Marque:  Thermo Scientific™ 27-1604-12

12.88 EUR valable jusqu'au 2024-12-20
Utilisez le code promo "21651" pour bénéficier de cette offre.


Code produit. 17947122

  • 15.90€ / 0.50g

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Description

Description

2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-fluorocytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C41H49N5FO8P
Base: C
Base Protection: Ac
Formula weight: 789.8 g/mol
CAS number: 159414-99-0
HPLC purity: >98%
31P NMR purity: ≥98%

TRUSTED_SUSTAINABILITY
Spécification

Spécification

Synthétiseurs MerMade
Conserver dans le congélateur (à -20°C ou moins).
2in-fluoro modifié, déprotection rapide
98 %
Phosphoramidite
ARN
Poudre
CEP 2in-fluoro-Ac-C
Cytidine (C)
Température ambiante
0.5 g
TheraPure™
TheraPure™
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Usage exclusivement réservé à la recherche. Ne pas utiliser pour des procédures de diagnostic.